Cochrane · systematic review · CD004349
Blood pressure targets in adults with hypertension
Arguedas, JA, Leiva, V, Wright, JM · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
HypertensionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 66.7%Moderate 1 · 16.7%High 1 · 16.7%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Lower BP target compared to standard BP target for hypertension
Population: adult patients with hypertension
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total mortality Lower BP target vs standard BP target | RR 0.95 [0.86, 1.05] | NR | High |
Total serious adverse events№ of participants: 18165(6 RCTs) Lower BP target vs standard BP target | RR 1.04 [0.99, 1.08] | NR | Moderate |
Myocardial infarction№ of participants: 38,198(8 RCTs) Lower BP target vs standard BP target | RR 0.84 [0.73, 0.96] | NR | Low |
Stroke№ of participants: 37,087(7 RCTs) Lower BP target vs standard BP target | RR 0.88 [0.77, 1.01] | NR | Low |
Congestive heart failure№ of participants: 15,859(5 RCTs) Lower BP target vs standard BP target | RR 0.75 [0.6, 0.92] | NR | Low |
Other serious adverse events Lower BP target vs standard BP target | RR 1.44 [1.32, 1.59] | NR | Low |