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What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 21 findings · 9 reviews · ENT

No studies found 12 · 57.1%GRADE not reported 0 · 0%Very low 8 · 38.1%Low 0 · 0%Moderate 1 · 4.8%High 0 · 0%

Intervention not reported

Serious complications · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics vs no treatment or placebo on top of topical antibiotics

Serious complications ‐ mastoid abscess measured at 12 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…

It is very uncertain whether systemic antibiotics changes serious complications ‐ mastoid abscess measured at 12 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).

1 finding from 1 review

Topical antibiotics with steroids vs topical antibiotics

Serious complications (including intracranial complications, extracranial complications and death) · people (of any age) with chronic suppurative otitis media or ear discharge

The review found no eligible studies for this question.

2 findings from 1 review

Intervention not reported

Adverse events, complications and morbidity associated with (adeno)tonsillectomy and comparators Expressed as the proportion of children experiencing a serious adverse event [7 months] · children with obstructive sleep‐disordered breathing
1 finding from 1 review