Acyclovir + calamine + cetirizine vs calamine + cetirizine
Serious adverse events, i.e. serious enough to require withdrawal of the treatment · pityriasis rosea
1 finding from 1 review
- no estimate extracted1 study · 24 participantsLow
Findings
What do systematic reviews say?
254 questions · 255 findings · 98 reviews
No studies found 91 · 35.7%GRADE not reported 15 · 5.9%Very low 85 · 33.3%Low 36 · 14.1%Moderate 21 · 8.2%High 7 · 2.7%
Acyclovir vs erythromycin
Serious adverse events, i.e. serious enough to require withdrawal of the treatment · pityriasis rosea
1 finding from 1 review
- no estimate extracted1 study · 30 participantsModerate
Erythromycin vs placebo
Serious adverse events, i.e. serious enough to require withdrawal of the treatment · pityriasis rosea
1 finding from 1 review
- no estimate extracted1 study · 34 participantsModerate
Oral propranolol vs placebo
Adverse events experienced at short or long term ‐ Serious adverse events 24 weeks' · infantile haemangiomas (strawberry birthmarks) of the skin
Oral propranolol showed no clear difference in adverse events experienced at short or long term ‐ Serious adverse… compared with placebo (low certainty).
1 finding from 1 review
- RR 1.05 [0.33, 3.39]3 studies · 509 participantsLow
Chemical peeling vs placebo or no treatment
Serious or severe adverse events N of participants with positive severe adverse events · people with acne scars
It is very uncertain whether chemical peeling changes serious or severe adverse events N of participants with positive… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
- RR 5.45 [0.33, 90.14]1 study · 58 participantsVery low
Intervention not reported
Adverse events a. Serious adverse events b. Discontinuation of trial because of adverse events · obese children and adolescents
The intervention showed no clear difference in adverse events a. Serious adverse events b. Discontinuation of trial… (low certainty).
1 finding from 1 review
- Drug interventions for the treatment of obesity in children and adolescents 2016 · Cochrane Headline outcomes onlyRR 1.43 [0.63, 3.25]5 studies · 1347 participantsLow
Mood stabilisers vs placebo
Non‐serious adverse events Timing of outcome assessment: end of treatment · patients with borderline personality disorder
It is very uncertain whether mood stabilisers changes non‐serious adverse events Timing of outcome assessment: end of… compared with placebo (very low certainty).
1 finding from 1 review
- Pharmacological interventions for people with borderline personality disorder 2022 · Cochrane Headline outcomes onlyRR 0.841 study · 276 participantsVery low
Intervention not reported
Serious adverse events (such as donor site morbidity, failure of graft including re‐rupture) at 2 years · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)
1 finding from 1 review
- Surgical versus conservative interventions for treating anterior cruciate ligament injuries 2016 · Cochrane Headline outcomes onlyno estimate extracted1 study · 121 participantsGRADE not reported
Palliative care vs usual care
Adverse effects: at least one serious adverse event · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…
Palliative care showed no clear difference in serious adverse events Assessed by: number of participants… compared with usual care (low certainty).
1 finding from 1 review
- Palliative care interventions for people with multiple sclerosis 2019 · Cochrane Headline outcomes onlyRR 0.97 [0.44, 2.12]1 study · 76 participantsLow
Antipsychotics vs placebo
Non‐serious adverse events Timing of outcome assessment: end of treatment · patients with borderline personality disorder
It is very uncertain whether antipsychotics changes non‐serious adverse events Timing of outcome assessment: end of… compared with placebo (very low certainty).
1 finding from 1 review
- Pharmacological interventions for people with borderline personality disorder 2022 · Cochrane Headline outcomes onlyRR 1.075 studies · 814 participantsVery low
Topical timolol vs placebo
Adverse events experienced at short or long term ‐ Serious cardiovascular adverse events ‐ bradycardia 24 weeks' · infantile haemangiomas (strawberry birthmarks) of the skin
1 finding from 1 review
- no estimate extracted1 study · 41 participantsLow
Calcineurin inhibitor vs IV cyclophosphamide
Adverse events: treatment failure (non response, serious infection, persistently elevated creatinine) at 6 months · idiopathic steroid‐resistant nephrotic syndrome in children
Calcineurin inhibitor probably leads to lower adverse events: treatment failure at 6 months (non response, serious… compared with IV cyclophosphamide (moderate certainty).
1 finding from 1 review
- Interventions for idiopathic steroid‐resistant nephrotic syndrome in children 2019 · Cochrane Headline outcomes onlyRR 0.32 [0.18, 0.58]1 study · 124 participantsModerate
Intervention not reported
Serious adverse events for all placebos compared with wait‐list or no treatment (Spontaneous reporting of dichotomous outcomes) (Post‐treatment) · patients with mental health disorders
It is very uncertain whether the intervention changes serious adverse events for all placebos compared with wait‐list or… (very low certainty).
1 finding from 1 review
- Control interventions in randomised trials among people with mental health disorders 2022 · Cochrane Headline outcomes onlyno estimate extracted11 studies · 517 participantsVery low
Intervention not reported
Non‐serious adverse events for all placebos compared with wait‐list or no treatment (Spontaneous reporting of dichotomous outcomes) (Post‐treatment) · patients with mental health disorders
It is very uncertain whether the intervention changes non‐serious adverse events for all placebos compared with wait‐list… (very low certainty).
1 finding from 1 review
- Control interventions in randomised trials among people with mental health disorders 2022 · Cochrane Headline outcomes onlyRD 0.0314 studies · 590 participantsVery low