Cochrane · systematic review · CD012936
Palliative care interventions for people with multiple sclerosis
Latorraca, COC, Martimbianco, ALC, Pachito, DV, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Multiple Sclerosis and Rare Diseases of the CNSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
3
No studies
4
Included studies
NR
No studies 4 · 57.1%Ungraded 0 · 0%Very low 1 · 14.3%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Palliative care compared to usual care for people with multiple sclerosis (≥ six months post‐intervention)
Population: Adults people with multiple sclerosis (including RRMS, SPMS, PPMS, PRMS)1
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Health‐related quality of life Assessed by: SeiQoL‐DW (higher scores mean better quality of life) Palliative care vs usual care | no estimate extracted | 1 study · 58 participants | Very low Downgraded: risk of bias, imprecision |
Serious adverse events Assessed by: number of participants presenting at least one serious adverse event Palliative care vs usual care | RR 0.97 [0.44, 2.12] | 1 study · 76 participants | Low Downgraded: risk of bias, imprecision |
Hospital admission Assessed by: number of participants admitted in hospital Palliative care vs usual care | RR 0.78 [0.24, 2.52] | 1 study · 76 participants | Low Downgraded: risk of bias, imprecision |
Fatigue ‐ Not reported at long term Palliative care vs usual care | no estimate extracted | NR | No studies |
Disability ‐ Not reported at long term Palliative care vs usual care | no estimate extracted | NR | No studies |
Anxiety ‐ Not reported at long term Palliative care vs usual care | no estimate extracted | NR | No studies |
Depression ‐ Not reported at long term Palliative care vs usual care | no estimate extracted | NR | No studies |