What do systematic reviews say?

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery plus WBRT

• Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 14 participants
  Very low

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery

• Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  Very low

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

• Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Summary of findings: Molecular‐targeted therapy plus chemotherapy vs chemotherapy alone

• Molecular‐targeted first‐line therapy for advanced gastric cancer 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 53 participants
  Very low

PFMT added to drug therapy vs drug therapy alone

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 101 participants
  Low

Psychotherapy preceded by motivational interviewing vs psychotherapy alone

• Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 47 participants
  Very low

Exercise therapy plus antidepressants vs antidepressants alone

The review found no eligible studies for this question.

• Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Platinum‐sensitive recurrent EOC: PARPi monotherapy vs placebo (maintenance therapy)

• Poly(ADP‐ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 339 participants
  Moderate

Psychological therapies (cognitive therapy) vs placebo

The review found no eligible studies for this question.

• Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes

  short-term (up to 3 months)
  SoF8: No included study reported change in QoL.
  0 studies
  No studies found

Low‐level laser therapy vs placebo

It is very uncertain whether electromagnetic radiation (low-level laser therapy) changes change in quality of life (QoL) compared with placebo (very low certainty).

• Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes

  short-term (up to 3 months)
  MD -5.24 [-7.38, -3.09]
  1 study · 58 participants
  Very low

Cognitive behavioural therapy as vs standard‐of‐care therapy

• Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

Antihypertensive drug therapy vs placebo

• Pharmacological treatment of hypertension in people without prior cerebrovascular disease for the prevention of… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 15795 participants
  Very low

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 208 participants
  Very low

CBT vs control

• Psychological interventions for women with non‐metastatic breast cancer 2023 · Cochrane Headline outcomes only
  no estimate extracted
  20 studies · 1747 participants
  Low

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 147 participants
  Very low

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 44 participants
  Low

Serenoa repens in combination with other phytotherapy vs placebo or no intervention

• Serenoa repens for the treatment of lower urinary tract symptoms due to benign prostatic enlargement 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 265 participants
  Very low

CBT vs usual care

Cognitive‐behavioural therapy probably leads to higher health‐related quality of life Investigators measured health‐related… compared with usual care (moderate certainty).

• Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
  SMD 0.51 [0.19, 0.83]
  4 studies · 230 participants
  Moderate

CANNABIS REDUCTION: ADJUNCT PSYCHOLOGICAL THERAPY vs treatment

• Cannabis and schizophrenia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 49 participants
  Moderate

Summary of findings ‐ dual therapy: lumacaftor plus ivacaftor (once daily) vs placebo

• Corrector therapies (with or without potentiators) for people with cystic fibrosis with class II CFTR gene variants… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1061 participants
  Moderate