Findings

What do systematic reviews say?

13 questions · 16 findings · 9 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

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No studies found 9 · 56.3%GRADE not reported 1 · 6.3%Very low 4 · 25%Low 1 · 6.3%Moderate 1 · 6.3%High 0 · 0%

Ultra‐radical (extensive) surgery vs surgery

Quality of life · women with stage IIIc or IV ovarian cancer

The review found no eligible studies for this question.

1 finding from 1 review

Ultra‐radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

iMRI image‐guided surgery vs surgery

Quality of life · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

5‐ALA image‐guided surgery vs surgery

Quality of life · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery plus WBRT

Health‐related quality of life (HRQoL) · people with single or solitary brain metastasis

1 finding from 1 review

Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery

Health‐related quality of life (HRQoL) · people with single or solitary brain metastasis

1 finding from 1 review

Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Very low

Neuronavigation image‐guided surgery vs surgery

Quality of life · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Radiosurgery alone vs WBRT and radiosurgery

Quality of lifeNo. of participants: 271(2 RCTs) · patients with newly diagnosed multiple brain metastases

1 finding from 1 review

Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Psychosocial intervention to improve sexual health vs no intervention

Quality of life · adult women, 18 years of age or older, who tested positive for a pathogenic mutation in BRCA1 or BRCA2 and who had had risk‐reducing surgery

1 finding from 1 review

Interventions to improve psychosocial well‐being in female BRCA‐mutation carriers following risk‐reducing surgery 2019 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Edaravone plus corticosteroids vs corticosteroids

Quality of life · people previously treated with radiosurgery or fractionated radiotherapy to the brain or head and neck region with a diagnosis of brain…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of brain radionecrosis after radiotherapy or radiosurgery 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: bevacizumab vs placebo

Quality of life · people previously treated with radiosurgery or fractionated radiotherapy to the brain or head and neck region with a diagnosis of brain…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of brain radionecrosis after radiotherapy or radiosurgery 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mindfulness‐based stress reduction training vs usual care

Menopause‐specific quality of life (quality of life) · female BRCA carriers post‐risk‐reducing surgery

1 finding from 1 review

Interventions to improve psychosocial well‐being in female BRCA‐mutation carriers following risk‐reducing surgery 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Very low

Intervention not reported

Health related quality of life · Patients with brain metastases

1 finding from 1 review

Surgery or radiosurgery plus whole brain radiotherapy versus surgery or radiosurgery alone for brain metastases 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 436 participants
Low

Hormone replacement therapy (HRT) vs no HRT

Quality of life: 1. General quality of life

1 finding from 1 review

Hormone replacement therapy after surgery for epithelial ovarian cancer 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 75 participants
Very low