Cochrane · systematic review · CD012894

Interventions to improve psychosocial well‐being in female BRCA‐mutation carriers following risk‐reducing surgery

Jeffers, L, Reid, J, Fitzsimons, D, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 21.4%Very low 11 · 78.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Mindfulness‐based stress reduction training versus usual care for female BRCA carriers post‐risk‐reducing surgery

Population: female BRCA carriers post‐risk‐reducing surgery
8 questions
OutcomeEffectEvidenceStatus / GRADE
Menopause‐specific quality of life (quality of life)
Mindfulness‐based stress reduction training vs usual care
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Sexual function (sexual function)
Mindfulness‐based stress reduction training vs usual care
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Sexual distress (sexual distress)
Mindfulness‐based stress reduction training vs usual care
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Vasomotor symptoms (vasomotor)
Mindfulness‐based stress reduction training vs usual care
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Psychosocial (psychosocial)
Mindfulness‐based stress reduction training vs usual care
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Physical symptoms (physical)
Mindfulness‐based stress reduction training vs usual care
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Sexual symptoms (sexual)
Mindfulness‐based stress reduction training vs usual care
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Body image (body image)
Mindfulness‐based stress reduction training vs usual care
no estimate extracted0 studies · 0 participantsUngraded

Psychosocial intervention to improve sexual health versus no intervention for adult women, 18 years of age or older, who tested positive for a pathogenic mutation in BRCA1 or BRCA2 and who had had risk‐reducing surgery

Population: adult women, 18 years of age or older, who tested positive for a pathogenic mutation in BRCA1 or BRCA2 and who had had risk‐reducing surgery
6 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life
Psychosocial intervention to improve sexual health vs no intervention
no estimate extracted0 participantsUngraded
Sexual function
Psychosocial intervention to improve sexual health vs no intervention
no estimate extracted1 study · 34 participantsVery low
Body image
Psychosocial intervention to improve sexual health vs no intervention
no estimate extracted0 participantsUngraded
Sexual self‐efficacy scale
Psychosocial intervention to improve sexual health vs no intervention
no estimate extracted1 study · 37 participantsVery low
Sexual knowledge
Psychosocial intervention to improve sexual health vs no intervention
no estimate extracted1 study · 36 participantsVery low
Participant satisfaction
Psychosocial intervention to improve sexual health vs no intervention
no estimate extracted1 study · 37 participantsVery low