Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

725 questions · 738 findings · 261 reviews

No studies found 403 · 54.6%GRADE not reported 61 · 8.3%Very low 124 · 16.8%Low 101 · 13.7%Moderate 45 · 6.1%High 4 · 0.5%

Neurodynamic mobilisation vs no treatment

Short‐term improvement in functional ability or health‐related quality of life (hand function) (three months or less) · People with carpal tunnel syndrome on a waiting list for carpal tunnel release

It is very uncertain whether neurodynamic mobilisation changes short‐term improvement in functional ability or health‐related… compared with no treatment (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Anger management vs waiting list control

Quality of life ‐ self reported: Comprehensive Quality of Life Scale: Intellectual Disability (COMQoL‐ID: Post‐treatment · outwardly aggressive behaviour in people with intellectual disability
1 finding from 1 review

Intervention not reported

General health‐related quality of life: SF‐36 physical component score (range 0 to 100; higher score = better health state) at 2 years · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)
1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Health‐related quality of life (physical) · adults with acute acromioclavicular dislocation of the shouldera
1 finding from 1 review

Pyridoxine vs placebo

Severity, reduction or cessation in nausea/vomiting 2. Quality of life outcomes 3. Pregnancy complications 4. Adverse fetal/neonatal outcomes · Pregnant women with hyperemesis gravidarum

The review found no eligible studies for this question.

1 finding from 1 review

Doxycycline vs prednisolone

Quality of life (DLQI) adjusted for baseline DLQI, disease severity, age, Karnovsky score, baseline versus week 52. A lower score is more favourable. · bullous pemphigoid
1 finding from 1 review