What do systematic reviews say?

Leg Club vs nurse home visits

• Interventions for helping people adhere to compression treatments for venous leg ulceration 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 52 participants
  Low

Oral plus nebulised antibiotics vs oral antibiotics plus nebulised placebo

• Interventions for the eradication of meticillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Very low

Lanadelumab vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 68 participants
  Low

Intervention not reported

The intervention showed no clear difference in quality of life at 6 months Assessed by European Quality of Life‐15 (low certainty).

• Environmental and behavioural interventions for reducing physical activity limitation and preventing falls in older… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 59 participants
  Low

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

The review found no eligible studies for this question.

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
  No data were available for this patient-reported outcome in the single included trial.
  0 studies
  No studies found

C1 esterase inhibitor vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 36 participants
  Low

Nanofiltered C1 esterase inhibitor vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

Intervention vs usual care

• Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 77 participants
  Low

Intervention vs usual care

• Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 70 participants
  Low

Intervention not reported

The intervention showed no clear difference in health‐related quality of life scores, measured by SF‐36 (range 0 to… (low certainty).

• Surgical versus medical interventions for chronic rhinosinusitis with nasal polyps 2014 · Cochrane Headline outcomes only
  MD 0.6
  1 study · 95 participants
  Low

Selenium vs no intervention

• Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes

  6 weeks after end of RT
  Insufficient evidence of differences for loss of taste or dysphagia; data largely unusable (no standard deviations). Ageusia milder in selenium group (not significant); dysphagia significant only at week 7 (P = 0.05)…
  1 study
  GRADE not reported

Intervention diet vs control diet

• Dietary interventions for induction and maintenance of remission in inflammatory bowel disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 12 participants
  Very low

Berotralstat vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 130 participants
  Moderate

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

The review found no eligible studies for this question.

• Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Intervention not reported

• Drug interventions for the treatment of obesity in children and adolescents 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 86 participants
  Low

Plasma‐derived C1 esterase inhibitor vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  Low

Avoralstat vs placebo

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 93 participants
  Moderate

Corticosteroids vs promethazine

The review found no eligible studies for this question.

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention diet vs control diet

• Dietary interventions for induction and maintenance of remission in inflammatory bowel disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 14 participants
  Very low

Combinations of conservative treatments vs no treatment, sham treatment or verbal/written instruction

Combinations of conservative treatments showed no clear difference in condition‐specific quality of life: using validated questionnaires,… compared with no treatment, sham treatment or verbal/written instruction (moderate certainty).

• Conservative interventions for managing urinary incontinence after prostate surgery 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 788 participants
  Moderate