Findings

What do systematic reviews say?

7 questions · 7 findings · 3 reviews · Pain, Palliative and Supportive Care

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 28.6%Low 2 · 28.6%Moderate 2 · 28.6%High 1 · 14.3%

Pregabalin vs placebo

Patient Global Impression of Change much or very much improved · children and adolescents with chronic non‐cancer pain

1 finding from 1 review

Antiepileptic drugs for chronic non‐cancer pain in children and adolescents 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 107 participants
Very low

Pregabalin vs placebo at end of treatment

Patient Global Impression of Change much or very much improved · patients with fibromyalgia

Pregabalin leads to higher patient Global Impression of Change of 'much' or 'very much' improved compared with placebo at end of treatment (high certainty).

1 finding from 1 review

Anticonvulsants for fibromyalgia 2013 · Cochrane Headline outcomes only
RR 1.38 [1.23, 1.55]
5 studies · 3183 participants
High

Pregabalin 600 mg vs placebo

Patient Global Impression of Change much or very much improved · adults with moderate or severe pain associated with postherpetic neuralgia

1 finding from 1 review

Pregabalin for neuropathic pain in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Pregabalin 300 mg vs placebo

Patient Global Impression of Change much or very much improved · adults with moderate or severe pain associated with painful diabetic neuropathy

1 finding from 1 review

Pregabalin for neuropathic pain in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1050 participants
Moderate

Pregabalin 300 mg vs placebo

PGIC very much improved · adults with moderate or severe pain associated with painful diabetic neuropathy

1 finding from 1 review

Pregabalin for neuropathic pain in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 501 participants
Low

Pregabalin 600 mg vs placebo

Patient Global Impression of Change much or very much improved · adults with moderate or severe pain associated with painful diabetic neuropathy

1 finding from 1 review

Pregabalin for neuropathic pain in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 537 participants
Moderate

Pregabalin 300 mg vs placebo

Patient Global Impression of Change much or very much improved · adults with moderate or severe pain associated with postherpetic neuralgia

1 finding from 1 review

Pregabalin for neuropathic pain in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 568 participants
Low