Question · asked by 1 review

Pregabalin 300 mg vs placebo: Patient Global Impression of Change much or very much improved

Population
adults with moderate or severe pain associated with painful diabetic neuropathy
Intervention
Pregabalin 300 mg
Comparison
placebo
Outcome
Patient Global Impression of Change much or very much improved

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Pregabalin 300 mg vs placebo
Patient Global Impression of Change ‐ much or very much improved · adults with moderate or severe pain associated with painful diabetic neuropathy
Pregabalin for neuropathic pain in adults (2019) · Cochrane Headline outcomes only
no estimate extracted5 studies · 1050 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pregabalin for neuropathic pain in adults
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.