Findings

What do systematic reviews say?

10 questions · 10 findings · 4 reviews · Pain, Palliative and Supportive Care

No studies found 2 · 20%GRADE not reported 0 · 0%Very low 6 · 60%Low 1 · 10%Moderate 1 · 10%High 0 · 0%

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

Tramadol showed no clear difference in number of patients with moderate to severe pain (PACU) compared with pethidine (low certainty).

1 finding from 1 review

Tramadol for postoperative pain treatment in children 2015 · Cochrane Headline outcomes only
RR 0.64 [0.36, 1.16]
2 studies · 94 participants
Low

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

The review found no eligible studies for this question.

1 finding from 1 review

Tramadol for postoperative pain treatment in children 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

1 finding from 1 review

Tramadol for postoperative pain treatment in children 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

The review found no eligible studies for this question.

1 finding from 1 review

Tramadol for postoperative pain treatment in children 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

1 finding from 1 review

Tramadol for postoperative pain treatment in children 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low

Pain no worse than mild at one or two weeks (or equivalent) · people with cancer pain

1 finding from 1 review

Tramadol with or without paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 227 participants
Very low

At least 30% reduction in pain · people with cancer pain

1 finding from 1 review

Tramadol with or without paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 227 participants
Very low

At least 50% reduction in pain · people with cancer pain

1 finding from 1 review

Tramadol with or without paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 227 participants
Very low

Participant‐reported pain relief of 50% or greater · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single fixed‐dose oral dexketoprofen plus tramadol for acute postoperative pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 748 participants
Moderate

Number of patients with moderate/severe pain (1 hour postoperatively) · children undergoing surgery

1 finding from 1 review

Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low