Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 21 findings · 7 reviews

No studies found 4 · 19%GRADE not reported 0 · 0%Very low 7 · 33.3%Low 4 · 19%Moderate 6 · 28.6%High 0 · 0%

Tramadol vs placebo

At least 50% reduction in pain · adults with neuropathic pain

Tramadol may leads to higher at least 50% reduction in pain compared with placebo (low certainty).

1 finding from 1 review

Tramadol vs pethidine

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

Tramadol showed no clear difference in number of patients with moderate to severe pain (PACU) compared with pethidine (low certainty).

1 finding from 1 review

Tramadol vs fentanyl

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

The review found no eligible studies for this question.

1 finding from 1 review

Tramadol vs morphine

Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery

The review found no eligible studies for this question.

1 finding from 1 review