Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 10 reviews · Breast Cancer

No studies found 1 · 7.1%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 28.6%High 9 · 64.3%

Taxane followed by anthracyclines vs anthracyclines followed by taxane

Overall survival ( · neoadjuvant therapy for early breast cancer

Taxane followed by anthracyclines showed no clear difference in overall survival ( compared with anthracyclines followed by taxane (moderate certainty).

1 finding from 1 review

Intervention not reported

Overall survival (OS) · HER2‐positive early breast cancer patients

The intervention leads to lower overall survival (OS) (high certainty).

1 finding from 1 review

High‐dose chemotherapy vs chemotherapy without bone marrow transplant or stem cell rescue

Overall survival at 5‐year · women with early poor prognosis breast cancer

High‐dose chemotherapy showed no clear difference in overall survival at 5‐year compared with chemotherapy without bone marrow transplant or stem cell rescue (high certainty).

1 finding from 1 review

Capecitabine‐containing regimens vs non‐capecitabine‐containing regimens or no chemotherapy

Overall survival: Median length of · patients with early breast cancer

Capecitabine‐containing regimens probably leads to lower overall survival (OS)median compared with non‐capecitabine‐containing regimens or no chemotherapy (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Overall survival (OS) · women with breast cancer and one to three positive lymph nodes

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) probably leads to lower overall survival (OS) compared with no PMRT (moderate certainty).

1 finding from 1 review