Question · asked by 1 review

Capecitabine‐containing regimens vs non‐capecitabine‐containing regimens or no chemotherapy: Overall survival: Median length of

Capecitabine‐containing regimens probably leads to lower overall survival (OS)median compared with non‐capecitabine‐containing regimens or no chemotherapy (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Capecitabine‐containing regimens vs non‐capecitabine‐containing regimens or no chemotherapy
Overall survival (OS)median · people with early breast cancer
Capecitabine‐containing regimens probably leads to lower overall survival (OS)median compared with non‐capecitabine‐containing regimens or no chemotherapy (moderate certainty).
Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer (2021) · Cochrane Headline outcomes only
HR 0.89 [0.81, 0.98]8 studies · 13547 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.