It is very uncertain whether embryo culture supernatant injection changes multiple pregnancy compared with no intervention (very low certainty).
It is very uncertain whether human chorionic gonadotropin (hCG) injection changes multiple pregnancy rate compared with no treatment (very low certainty).
It is very uncertain whether intrauterine infusion/injection of autologous platelet‐rich plasma changes adverse events: multiple pregnancy compared with no intervention or placebo (very low certainty).
Repeated single embryo transfer (mixed policies) probably leads to lower multiple pregnancy compared with multiple embryo transfer (moderate certainty).
Single probably leads to lower multiple pregnancy compared with multiple embryo transfer (moderate certainty).
The review found no eligible studies for this question.
Day 3 showed no clear difference in multiple pregnancy rate per woman compared with day 2 embryo transfer following IVF or ICSI (moderate certainty).
Summary of findings table ‐ ICSI showed no clear difference in multiple Pregnancy compared with c‐IVF (moderate certainty).
GnRHa depot showed no clear difference in multiple pregnancy rates compared with gnRHa daily injection (low certainty).
Assisted hatching may leads to higher multiple pregnancy rate per woman randomised compared with no assisted hatching (low certainty).