Cochrane · systematic review · CD001894
Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI))
Lacey, L, Hassan, S, Franik, S, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsAssisted hatching compared to no assisted hatching for women undergoing assisted conception
Population: women undergoing assisted conception
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live births per woman randomised Assisted hatching vs no assisted hatching | OR 1.09 [0.92, 1.29] | 14 studies · 2849 participants | Low Downgraded: risk of bias, publication bias |
Multiple pregnancy rate per woman randomised Assisted hatching vs no assisted hatching | OR 1.38 [1.13, 1.68] | 18 studies · 4308 participants | Low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Clinical pregnancy rate per woman randomised Assisted hatching vs no assisted hatching | OR 1.2 [1.09, 1.33] | 39 studies · 7249 participants | Low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Miscarriage rate per woman randomised Assisted hatching vs no assisted hatching | OR 1.13 [0.82, 1.56] | 17 studies · 2810 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |