Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

398 questions · 434 findings · 166 reviews

No studies found 95 · 21.9%GRADE not reported 31 · 7.1%Very low 91 · 21%Low 110 · 25.3%Moderate 78 · 18%High 29 · 6.7%

Community health educational interventions vs control

Neonatal mortality · developing countries

Community health educational interventions may leads to lower neonatal mortality compared with control (low certainty).

2 findings from 1 review

Higher circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower circulating 25-hydroxyvitamin D (25(OH)D) concentration

All cause mortality (in CKD patients) · Participants in observational studies

The meta-analysis of observational studies reported a RR of 0.88 (95% CI 0.81 to 0.93) for higher versus lower circulating vitamin D concentration.

1 finding from 1 review

Subcutaneous unfractionated heparin vs low molecular weight heparin

All‐cause mortality (7 days ‐ 3 months) · people aged ≥ 18 years with a diagnosis of new or recurrent VTE

Subcutaneous unfractionated heparin showed no clear difference in all‐cause mortality (7 days ‐ 3 months) compared with low molecular weight heparin (low certainty).

1 finding from 1 review

Moderate vs low protein concentration of human milk fortifier

Mortality during period of therapy · preterm infants

Moderate showed no clear difference in mortality during the intervention period compared with low protein concentration of human milk fortifier; GRADE not reported.

1 finding from 1 review

External uterine compression (all methods) plus normal care vs normal care

Mortality due to bleeding ‐ not reported · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601

The review found no eligible studies for this question.

1 finding from 1 review

Community health educational interventions vs control

Perinatal mortality · developing countries

Community health educational interventions probably leads to lower perinatal mortality compared with control (moderate certainty).

2 findings from 1 review

Intervention not reported

Perinatal mortality · women with a previous stillbirth of > 20 weeks' gestation who are pregnant or considering a subsequent pregnancy

It is very uncertain whether the intervention changes perinatal mortality (very low certainty).

1 finding from 1 review