Findings

What do systematic reviews say?

20 questions · 24 findings · 8 reviews

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No studies found 17 · 70.8%GRADE not reported 0 · 0%Very low 1 · 4.2%Low 1 · 4.2%Moderate 2 · 8.3%High 3 · 12.5%

Antibiotics vs no treatment or placebo on top of topical antibiotics

Health‐related quality of life ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 101 participants
Very low

Antibiotics vs no treatment or placebo on top of topical antibiotics

Health‐related quality of life · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

14 days on/off antibiotic regimen vs 28 days on/off antibiotic regimen

Health‐related quality of life · people with bronchiectasis

2 findings from 1 review

Intermittent prophylactic antibiotics for bronchiectasis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
High
Intermittent prophylactic antibiotics for bronchiectasis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
High

Topical antibiotics with steroids vs topical antibiotics

Health‐related quality of life · people (of any age) with chronic suppurative otitis media or ear discharge

The review found no eligible studies for this question.

2 findings from 1 review

Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs placebo/no treatment

Health‐related quality of life · patients with mucopurulent otorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antiseptics

Health‐related quality of life · schoolchildren with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment/placebo

Health‐related quality of life · children with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

Health‐related quality of life

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

28 days on/off antibiotic regimen vs 28 days on/off placebo regimen

Health‐related quality of life · people with bronchiectasis

2 findings from 1 review

Intermittent prophylactic antibiotics for bronchiectasis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate
Intermittent prophylactic antibiotics for bronchiectasis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

14 days on/off antibiotic regimen vs 14 days on/off placebo regimen

Health‐related quality of life · people with bronchiectasis

2 findings from 1 review

Intermittent prophylactic antibiotics for bronchiectasis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
High
Intermittent prophylactic antibiotics for bronchiectasis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Topical antibiotics with steroids vs placebo/no treatment

Health‐related quality of life · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs intramuscular gentamicin

Health‐related quality of life · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Health‐related quality of life · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Health‐related quality of life · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health‐related quality of life · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Quinolone vs aminoglycosides

Health‐related quality of life · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health‐related quality of life · patients undergoing orthognathic surgery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health‐related quality of life · patients undergoing orthognathic surgery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Linezolid vs vancomycin

Health‐related quality of life Maximum · neonates and children with hospital‐acquired pneumonia

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for hospital‐acquired pneumonia in neonates and children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cefepime vs ceftazidime

Health‐related quality of life Maximum · neonates and children with hospital‐acquired pneumonia

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for hospital‐acquired pneumonia in neonates and children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found