What do systematic reviews say?

Summary of findings: insulin degludec vs insulin glargine

• (Ultra‐)long‐acting insulin analogues for people with type 1 diabetes mellitus 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1042 participants
  Very low

Cognitive‐behavioural intervention vs controls

• Cognitive behavioural therapies for fibromyalgia 2013 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 1238 participants
  Low

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Serotonin noradrenaline reuptake inhibitors showed no clear difference in self‐reported health‐related quality of life (0‐100 scale) Higher… compared with placebo (low certainty).

• Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia 2018 · Cochrane Headline outcomes only
  no estimate extracted
  14 studies · 6861 participants
  Low

Surgical vs non‐surgical treatment

• Surgical versus non‐surgical interventions for displaced intra‐articular calcaneal fractures 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 192 participants
  Low

Parent‐only interventions vs minimal contact control

• Parent‐only interventions for childhood overweight or obesity in children aged 5 to 11 years 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 93 participants
  GRADE not reported

Preoperative education vs usual care

• Preoperative education for hip or knee replacement 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 109 participants
  Low

Intervention not reported

• Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1791 participants
  Very low

Intervention not reported

• Surgical versus conservative interventions for treating anterior cruciate ligament injuries 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 121 participants
  Low

Mobile bearing vs fixed bearing prosthesis

• Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplasty for postoperative… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 498 participants
  Low

Intervention not reported

The intervention showed no clear difference in health‐related quality of life (health status) COPD Assessment Tool.… (low certainty).

• Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Low

Ventilation feedback training plus exercise vs exercise

• Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 73 participants
  Moderate

Intervention not reported

• Early palliative care for adults with advanced cancer 2017 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 1028 participants
  Low

Intervention not reported

• Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Low

Eculizumab vs placebo

• Eculizumab for treating patients with paroxysmal nocturnal hemoglobinuria 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 87 participants
  Low

Intervention not reported

• Singing for adults with chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 52 participants
  Low

Home fall‐hazard reduction vs control (e.g. usual activities)

Home fall‐hazard reduction showed no clear difference in health‐related quality of life SMD was calculated from 4 studies… compared with control (e.g. usual care) (moderate certainty).

• Environmental interventions for preventing falls in older people living in the community 2023 · Cochrane Headline outcomes only
  SMD 0.09
  6 studies · 1848 participants
  Moderate

Assistive technology for vision improvement interventions vs usual care or attention control

Assistive technology for vision improvement interventions showed no clear difference in health‐related quality of life 1 trial of single‐lens glasses… compared with usual care or attention control (low certainty).

• Environmental interventions for preventing falls in older people living in the community 2023 · Cochrane Headline outcomes only
  MD 0.4
  1 study · 597 participants
  Low

Intervention not reported

• Singing for adults with chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 52 participants
  Low

Yoga vs an active intervention

• Yoga for treating urinary incontinence in women 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Dinutuximab‐containing immunotherapy vs usual care

The review found no eligible studies for this question.

• Anti‐GD2 antibody‐containing immunotherapy postconsolidation therapy for people with high‐risk neuroblastoma treated… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found