Cochrane · systematic review · CD011129
Early palliative care for adults with advanced cancer
Haun, MW, Estel, S, Rücker, G, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 12.5%Very low 3 · 37.5%Low 4 · 50%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Early palliative care for adults with advanced cancer
Population: patients with advanced cancer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Health‐related quality of life (HRQOL), SD units: measured on FACIT‐Pal, TOI of FACT‐Hep, TOI of FACT‐L, FACT‐G, McGill Quality of Life, FACIT‐Sp. Higher scores indicate better HRQOL. | no estimate extracted | 7 studies · 1028 participants | Low Downgraded: risk of bias |
Health‐related quality of life (HRQOL), natural units: measured on FACT‐G (from 0 to 108) | no estimate extracted | 7 studies · 1028 participants | Low Downgraded: risk of bias |
Survival: estimated with the unadjusted death hazard ratio | HR 0.85 | 4 studies · 800 participants | Very low Downgraded: risk of bias |
Depression, SD units: measured on CES‐D, HADS‐D, PHQ‐9. Higher scores indicate higher depressive symptom load. | no estimate extracted | 5 studies · 762 participants | Very low Downgraded: risk of bias |
Depression, natural units: measured on CES‐D (from 0 to 60). Higher scores indicate higher depressive symptom load | no estimate extracted | 5 studies · 762 participants | Very low Downgraded: risk of bias |
Symptom intensity, SD units: measured on ESAS, QUAL‐E Symptom Impact Subscale, SDS, RSC, LCS of FACT‐L, HCS of FACT‐Hep. Higher scores indicate higher symptom intensity. | no estimate extracted | 7 studies · 1054 participants | Low Downgraded: risk of bias |
Symptom intensity, natural units: measured on ESAS (from 0 to 900). | no estimate extracted | 7 studies · 1054 participants | Low Downgraded: risk of bias |
Adverse events | no estimate extracted | 7 studies · 1614 participants | Ungraded |