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Evidence found and GRADE certainty

108 questions · 115 findings · 61 reviews

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No studies found 22 · 19.1%GRADE not reported 4 · 3.5%Very low 23 · 20%Low 36 · 31.3%Moderate 21 · 18.3%High 9 · 7.8%

Remote monitoring plus usual care vs usual care

Mortality (all‐cause) · patients with chronic obstructive pulmonary disease

It is very uncertain whether remote monitoring plus usual care changes mortality (all‐cause) compared with usual care (very low certainty).

1 finding from 1 review

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

Cardiovascular mortality · patients with chronic heart failure with preserved ejection fraction
2 findings from 1 review

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

Cardiovascular mortality · adults (≥ 18 years of age) with a diagnosis of chronic heart failure with reduced ejection fraction (HFrEF)

Usual care with ivabradine showed no clear difference in mortality from cardiovascular causes ( compared with placebo, usual care, or no treatment (moderate certainty).

2 findings from 1 review

Glucocorticoid with cyclophosphamide plus usual care vs placebo or usual care

All‐cause mortality at final · people with moderate to severe oral paraquat poisoning

Glucocorticoid with cyclophosphamide plus usual care may leads to lower all‐cause mortality at final compared with usual care (with or without placebo) (low certainty).

2 findings from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

Death (all causes) · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower all‐cause mortality: Telemonitoring versus usual care compared with usual care ‐ all‐cause mortality (moderate certainty).

1 finding from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

All‐cause mortality: Structured telephone support versus usual care · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower all‐cause mortality: Structured telephone support versus usual care compared with usual care ‐ all‐cause mortality (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinical outcome: all‐cause mortality ATCS Plus versus usual care or usual community care at median · patients with heart failure

The intervention showed no clear difference in clinical outcome: all‐cause mortality ATCS Plus versus usual care or… (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinical outcome: cardiac mortality ATCS Plus, IVR versus usual care or usual community care at median · patients with heart failure

It is very uncertain whether the intervention changes clinical outcome: cardiac mortality ATCS Plus, IVR versus usual care… (very low certainty).

1 finding from 1 review

Professional oral care vs Usual oral care

Mortality (all‐cause) · Residents of nursing homes and other long-term care facilities
1 finding from 1 review
  • Oral care measures for preventing nursing home‐acquired pneumonia 2022 · Cochrane All outcomes
    12-30 months
    All-cause mortality, follow-up 12-30 months, 3764 (3 studies), Very low. Not pooled. Adachi RR 0.80 (0.40 to 1.58; 88); Juthani-Mehta HR 1.16 (0.88 to 1.53; 834); Zimmerman adjusted IRR 0.83 (0.61 to 1.12; 1606).…
    3 studies · 3764 participants
    Very low

Case management for integrated care vs usual care of older people living with frailty

All‐cause mortality · people aged 65 years and older living with frailty

Case management for integrated care showed no clear difference in mortality compared with usual care of older people living with frailty (low certainty).

1 finding from 1 review

Summary of findings: Any alternative model of care vs usual care

Has died · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)

Summary of findings: Any alternative model of care showed no clear difference in mortality: proportion of residents who died at longest compared with usual care (moderate certainty).

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

All‐cause mortality · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in mortality compared with placebo or usual care (moderate certainty).

1 finding from 1 review

Effects of practice‐based interprofessional collaboration (IPC) interventions on professional practice and healthcare outcomes vs usual care

Patient mortality, morbidity or complication rates · health and social care professionals involved in the delivery of health services and patient care

The review found no eligible studies for this question.

1 finding from 1 review