Findings

What do systematic reviews say?

29 questions · 29 findings · 8 reviews

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No studies found 8 · 27.6%GRADE not reported 0 · 0%Very low 11 · 37.9%Low 5 · 17.2%Moderate 4 · 13.8%High 1 · 3.4%

Intervention not reported

Mortality Beyond the early postoperative period (> 30 days) · participants with hydrocephalus

1 finding from 1 review

Ventriculo‐peritoneal shunting devices for hydrocephalus 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Very low

N‐acetylcysteine vs control

Early all‐cause mortality (≤ 3 months) Reported at: 30 days · adults with acute respiratory distress syndrome

It is very uncertain whether N‐acetylcysteine changes early all‐cause mortality (≤ 3 months) Reported at: 30 days compared with control (very low certainty).

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
RR 0.64 [0.32, 1.3]
1 study · 36 participants
Very low

Standardised formal neonatal resuscitation training (SFNRT) programme vs basic resuscitation training

Early neonatal mortality · Neonates delivered stratified by healthcare professionals involved in attending deliveries

Standardised formal neonatal resuscitation training (SFNRT) programme showed no clear difference in early neonatal mortality (mortality in the first 7 days of life) compared with basic resuscitation training (moderate certainty).

1 finding from 1 review

Standardised formal resuscitation training programmes for reducing mortality and morbidity in newborn infants 2015 · Cochrane Headline outcomes only
RR 0.88 [0.78, 1]
3 studies · 66162 participants
Moderate

Transmyocardial laser revascularization vs medical treatment

Early postoperative mortality Deaths in the 30 days after surgery · patients with refractory angina

Transmyocardial laser revascularization showed no clear difference in early postoperative mortality Deaths in the 30 days after surgery compared with medical treatment (high certainty).

1 finding from 1 review

Transmyocardial laser revascularization versus medical therapy for refractory angina 2015 · Cochrane Headline outcomes only
OR 1.19 [0.63, 2.24]
6 studies · 967 participants
High

Two per cent CHG vs alcohol hand sanitiser (61% alcohol and emollients)

Early neonatal mortality · Neonates and caregivers

The review found no eligible studies for this question.

1 finding from 1 review

Hand hygiene for the prevention of infections in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Alcohol‐based handrub vs usual care

Early neonatal mortality · Neonates and caregivers

It is very uncertain whether alcohol‐based handrub changes all‐cause mortality within the first seven days of life (early… compared with usual care (very low certainty).

1 finding from 1 review

Hand hygiene for the prevention of infections in neonates 2023 · Cochrane Headline outcomes only
RR 0.29 [0.01, 7]
1 study · 103 participants
Very low

Statins vs control

Early all‐cause mortality (≤ 3 months) Reported at: 28 days; 60 days; and during hospital stay · adults with acute respiratory distress syndrome

Statins showed no clear difference in early all‐cause mortality (≤ 3 months) Reported at: 60 days; and… compared with control (moderate certainty).

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
RR 0.99 [0.78, 1.26]
3 studies · 1344 participants
Moderate

Beta‐agonist vs control

Early all‐cause mortality (≤ 3 months) Reported at: 28 days; 60 days; and during hospital stay · adults with acute respiratory distress syndrome

Beta‐agonist showed no clear difference in early all‐cause mortality (≤ 3 months) Reported at: 28 days; 60… compared with control (moderate certainty).

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
RR 1.14 [0.91, 1.42]
3 studies · 646 participants
Moderate

Surfactants vs control

Early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90 days. Time point not reported in 4 studies · adults with acute respiratory distress syndrome

It is very uncertain whether surfactants changes early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90… compared with control (very low certainty).

1 finding from 1 review

Pharmacological agents for adults with acute respiratory distress syndrome 2019 · Cochrane Headline outcomes only
RR 1.08 [0.91, 1.29]
9 studies · 1338 participants
Very low