Question · asked by 1 review

Surfactants vs control: Early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90 days. Time point not reported in 4 studies

It is very uncertain whether surfactants changes early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90… compared with control (very low certainty).

What each review found

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FindingEffectStudiesGRADE certainty
Surfactants vs control
Early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90 days. Time point not reported in 4 studies · adults with acute respiratory distress syndrome
It is very uncertain whether surfactants changes early all‐cause mortality (≤ 3 months) Reported at: 28 days; and 90… compared with control (very low certainty).
Pharmacological agents for adults with acute respiratory distress syndrome (2019) · Cochrane Headline outcomes only
RR 1.08 [0.91, 1.29]9 studies · 1338 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacological agents for adults with acute respiratory distress syndrome
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.