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Evidence found and GRADE certainty

9 questions · 11 findings · 4 reviews · Dental caries

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No studies found 0 · 0%GRADE not reported 8 · 72.7%Very low 3 · 27.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Down syndrome vs Individuals without Down syndrome (healthy controls: siblings, schoolchildren or others)

Dental caries · Individuals of all ages

Individuals with Down syndrome had a lower prevalence of dental caries than those without (pooled OR 0.36, 95% CI 0.22 to 0.57; 2 studies; I2=0%); certainty of evidence not graded.

1 finding from 1 review

Presence of dental plaque vs Absence of dental plaque

Dental caries · Individuals in Ethiopia assessed for dental caries

The presence of dental plaque was not significantly associated with dental caries (OR 5.14, 95% CI 0.67 to 39.39); certainty not graded.

1 finding from 1 review

Poor / no tooth brushing habit vs Good tooth brushing habit

Dental caries · Individuals in East Africa assessed for dental caries

Poor tooth brushing was associated with significantly higher odds of dental caries (OR 1.967, 95% CI 1.205 to 3.211); certainty not graded.

1 finding from 1 review

Habit of tooth cleaning vs No habit of tooth cleaning

Dental caries · Individuals in Ethiopia assessed for dental caries

The habit of tooth cleaning was not significantly associated with dental caries (OR 0.71, 95% CI 0.17 to 2.96); certainty not graded.

1 finding from 1 review

Sweet food consumption (frequent) vs No/less frequent sweet food consumption

Dental caries · Individuals in Ethiopia assessed for dental caries

Sweet food consumption was associated with significantly higher odds of dental caries (OR 2.4, 95% CI 1.91 to 3.01); certainty not graded.

1 finding from 1 review

Frequent carbohydrate / sugary food intake vs Infrequent carbohydrate intake

Dental caries · Individuals in East Africa assessed for dental caries

Frequent carbohydrate intake was associated with significantly higher odds of dental caries (OR 1.575, 95% CI 1.13 to 3.051); certainty not graded.

1 finding from 1 review

Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs HIV-negative individuals

Dental caries · Children and adolescents (<18 years) living with HIV (CLWH)

In cross-sectional studies, children and adolescents with HIV on antiretroviral therapy had about twice the odds of dental caries versus HIV-negative peers (OR 2.04, 95% CI 1.21 to 3.42; very low certainty).

3 findings from 1 review