Early and late (day 1 to 28 after birth) higher vs lower sodium intake
Chronic lung disease · preterm or low birth weight infants
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Findings
What do systematic reviews say?
23 questions · 26 findings · 6 reviews
No studies found 2 · 7.7%GRADE not reported 7 · 26.9%Very low 6 · 23.1%Low 7 · 26.9%Moderate 4 · 15.4%High 0 · 0%
Late (seven days or more following birth) higher vs lower sodium intake
Chronic lung disease · preterm or low birth weight infants
It is very uncertain whether late (seven days or more following birth) higher changes chronic lung disease compared with lower sodium intake (very low certainty).
1 finding from 1 review
- RR 2.03 [0.8, 5.2]1 study · 49 participantsVery low
Early (less than seven days following birth) higher vs lower sodium intake
Chronic lung disease · preterm or low birth weight infants
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
HFNC vs continuous positive airway pressure (CPAP)
Chronic lung disease · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
1 finding from 1 review
- High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes onlyno estimate extracted1 study · 375 participantsGRADE not reported
High‐dose vs standard‐dose strategies
Bronchopulmonary dysplasia/chronic lung disease · preterm infants at risk for apnea
It is very uncertain whether high‐dose changes bronchopulmonary dysplasia/chronic lung disease (BPD) at 36 weeks'… compared with standard‐dose strategies (very low certainty).
1 finding from 1 review
- Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity 2023 · Cochrane Headline outcomes onlyRR 0.89 [0.61, 1.3]2 studies · 152 participantsVery low
High‐dose vs standard‐dose strategies
Bronchopulmonary dysplasia/chronic lung disease · preterm infants with or at risk for apnea of prematurity
It is very uncertain whether high‐dose changes bronchopulmonary dysplasia/chronic lung disease (BPD) at 36 weeks'… compared with standard‐dose strategies (very low certainty).
3 findings from 1 review
- Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity 2023 · Cochrane Headline outcomes onlyRR 0.72 [0.47, 1.11]3 studies · 333 participantsVery low
- Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity 2023 · Cochrane Headline outcomes onlyRR 0.68 [0.48, 0.97]1 study · 238 participantsLow
- Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity 2023 · Cochrane Headline outcomes onlyRR 0.75 [0.6, 0.94]5 studies · 723 participantsModerate
Rescue high‐frequency jet ventilation vs conventional ventilation
Chronic lung disease · preterm infants with severe pulmonary dysfunction
Rescue high‐frequency jet ventilation showed no clear difference in chronic lung disease at 28 days of birth (CLD 28 days) compared with conventional ventilation (low certainty).
2 findings from 1 review
- Rescue high‐frequency jet ventilation versus conventional ventilation for severe pulmonary dysfunction in preterm… 2015 · Cochrane Headline outcomes onlyRR 0.77 [0.54, 1.07]1 study · 97 participantsLow
- Rescue high‐frequency jet ventilation versus conventional ventilation for severe pulmonary dysfunction in preterm… 2015 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
HFNC vs low flow nasal cannula (LFNC)
Chronic lung disease · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
The review found no eligible studies for this question.
1 finding from 1 review
- High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth
Chronic lung disease · preterm infants
It is very uncertain whether lower changes chronic lung disease (36 weeks' corrected age) compared with higher oxygen concentrations titrated to target oxygen saturations… (very low certainty).
1 finding from 1 review
- Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm… 2018 · Cochrane Headline outcomes onlyRR 0.91 [0.72, 1.14]9 studies · 862 participantsVery low
nHFV vs NIPPV or NIV
Chronic lung disease · preterm infants with respiratory distress for initial respiratory support
nHFV may leads to lower chronic lung disease compared with nIPPV used (low certainty).
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyRR 0.63 [0.42, 0.95]5 studies · 307 participantsLow
nHFV vs HFNC
Chronic lung disease · preterm infants with respiratory distress for initial respiratory support
It is very uncertain whether nHFV changes chronic lung disease compared with HFNC (very low certainty).
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyRR 1.18 [0.46, 2.98]1 study · 37 participantsVery low
nHFV vs NCPAP
Chronic lung disease · ventilated preterm infants with planned extubation
nHFV may leads to lower chronic lung disease compared with nCPAP (low certainty).
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyRR 0.78 [0.67, 0.91]10 studies · 1829 participantsLow
nHFV vs invasive respiratory therapy
Chronic lung disease · preterm infants with respiratory distress for initial respiratory support
It is very uncertain whether nHFV changes chronic lung disease compared with invasive respiratory therapy (very low certainty).
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyRR 0.38 [0.09, 1.59]2 studies · 180 participantsVery low
nHFV vs NIPPV or NIV
Chronic lung disease · ventilated preterm infants with planned extubation
nHFV showed no clear difference in chronic lung disease compared with nIPPV (moderate certainty).
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyRR 0.88 [0.75, 1.04]4 studies · 1236 participantsModerate
nHFV vs nIPPV following failure of initial non‐invasive respiratory support
Chronic lung disease · ventilated preterm infants with failure of initial non‐invasive respiratory support
nHFV showed no clear difference in chronic lung disease compared with nIPPV following failure of initial non‐invasive respiratory support (low certainty).
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyRR 1.01 [0.7, 1.47]1 study · 39 participantsLow
nHFV vs NCPAP
Chronic lung disease · newborn (term* and preterm) infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in chronic lung disease compared with nCPAP used (low certainty).
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyRR 1.35 [0.8, 2.27]4 studies · 481 participantsLow
nHFV vs NCPAP
Death or chronic lung disease · newborn (term* and preterm) infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in death or chronic lung disease compared with nCPAP used (low certainty).
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyRR 2.5 [0.52, 12.01]1 study · 68 participantsLow
nHFV vs NIPPV or NIV
Death or chronic lung disease · preterm infants with respiratory distress for initial respiratory support
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported
nHFV vs HFNC
Death or chronic lung disease · preterm infants with respiratory distress for initial respiratory support
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported
nHFV vs NCPAP
Death or chronic lung disease · ventilated preterm infants with planned extubation
nHFV showed no clear difference in death or chronic lung disease compared with nCPAP (moderate certainty).
1 finding from 1 review
- Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes onlyRR 0.9 [0.77, 1.06]2 studies · 966 participantsModerate