Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

122 questions · 190 findings · 26 reviews

No studies found 0 · 0%GRADE not reported 171 · 90%Very low 11 · 5.8%Low 5 · 2.6%Moderate 3 · 1.6%High 0 · 0%

Not applicable (single-group prevalence) vs Not applicable (single-group prevalence)

Dental caries prevalence · Children (<18 years) with intellectual and developmental disabilities (IDD) in India

Dental caries affects about 64% of children with IDD in India (pooled prevalence 0.64, 95% CI 0.45-0.79; high heterogeneity; ungraded).

1 finding from 1 review

Disability (developmental, intellectual, or sensory) vs Persons without disabilities

Dental caries prevalence and severity · Persons with disabilities (children and adults with autism, Down syndrome, cerebral palsy, hearing impairment, or multiple disabilities)…

Dental caries prevalence and severity are high among persons with disabilities in Saudi Arabia (60% to over 80%), and the one comparative autism study reported significantly higher caries than controls; synthesized narratively (ungraded).

1 finding from 1 review

Combined antiretroviral therapy (cART) vs Monotherapy or dual antiretroviral therapy

Dental caries prevalence and severity · Children and adolescents (<18 years) living with HIV (CLWH)

No significant difference in dental caries/severity between ART regimens (very low certainty).

1 finding from 1 review

Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls

Dental caries prevalence · Children or adolescents

In permanent dentition, CLWH on ART had higher caries prevalence than healthy controls (OR 2.49, 95% CI 1.86 to 3.32; single study).

3 findings from 1 review