Question · asked by 1 review
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls: Dental caries prevalence
- Population
- Children or adolescents
- Intervention
- Living with HIV and undergoing antiretroviral therapy (ART/HAART)
- Comparison
- Healthy HIV-negative controls
- Outcome
- Dental caries prevalence
In permanent dentition, CLWH on ART had higher caries prevalence than healthy controls (OR 2.49, 95% CI 1.86 to 3.32; single study).
What each review found
Include earlier review versionsNo studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Dental caries prevalence (DMFT/dmft/DMFS/dmfs > 0) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point), HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal), Permanent dentition (DMFT > 0) In permanent dentition, CLWH on ART had higher caries prevalence than healthy controls (OR 2.49, 95% CI 1.86 to 3.32; single study). Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) All outcomes | OR 2.49 [1.86, 3.32] | 1 study · 724 participants | GRADE not reported |
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Dental caries prevalence (DMFT/dmft/DMFS/dmfs > 0) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point), HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal) Pooled analysis showed higher dental caries prevalence among CLWH on ART (OR 2.70, 95% CI 2.01 to 3.62), but the two studies were divergent and the authors concluded HIV/ART is not a predisposing factor to caries. Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) All outcomes | OR 2.70 [2.01, 3.62] | 2 studies · 1028 participants | GRADE not reported |
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Dental caries prevalence (DMFT/dmft/DMFS/dmfs > 0) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point), HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal), Primary dentition (dmft > 0) In primary dentition, CLWH on ART had higher caries prevalence than healthy controls (OR 1.93, 95% CI 1.34 to 2.79; single study). Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) All outcomes | OR 1.93 [1.34, 2.79] | 1 study · 564 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review and Meta-Analysis. 2022 All outcomes | Inception to 29 July 2022 | 21 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.