Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

115 questions · 120 findings · 58 reviews

No studies found 34 · 28.3%GRADE not reported 5 · 4.2%Very low 23 · 19.2%Low 32 · 26.7%Moderate 15 · 12.5%High 11 · 9.2%

Levosimendan vs dobutamine

All‐cause long‐term mortality: range 4 to 12 months · people with cardiogenic shock or low cardiac output syndrome

Levosimendan showed no clear difference in all‐cause long‐term mortality: range 4 to 12 months compared with dobutamine (low certainty).

1 finding from 1 review

Intramuscular injection of bone marrow mononuclear cells (BMMNC) vs control

All‐cause mortality ( · people with CLI who were not suitable for revascularisation and showed no improvement in response to the best standard therapy

It is very uncertain whether intramuscular injection of bone marrow mononuclear cells (BMMNC) changes all‐cause mortality ( compared with control (very low certainty).

1 finding from 1 review