Findings

What do systematic reviews say?

34 questions · 34 findings · 14 reviews

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No studies found 12 · 35.3%GRADE not reported 4 · 11.8%Very low 7 · 20.6%Low 5 · 14.7%Moderate 6 · 17.6%High 0 · 0%

Lidocaine vs dimethylammonium

All‐cause mortality · patients with myocardial infarction

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic lidocaine for myocardial infarction 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lidocaine vs aprindine

All‐cause mortality · patients with myocardial infarction

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic lidocaine for myocardial infarction 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lidocaine vs pirmenol

All‐cause mortality · patients with myocardial infarction

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic lidocaine for myocardial infarction 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lidocaine vs disopyramide

All‐cause mortality · patients with myocardial infarction

It is very uncertain whether lidocaine changes all‐cause mortality compared with disopyramide (very low certainty).

1 finding from 1 review

Prophylactic lidocaine for myocardial infarction 2015 · Cochrane Headline outcomes only
RR 1.39 [0.47, 4.13]
2 studies · 144 participants
Very low

Intervention not reported

All‐cause mortality · preterm or low birth weight infants

The intervention showed no clear difference in all‐cause mortality (moderate certainty).

1 finding from 1 review

Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants 2012 · Cochrane Headline outcomes only
RR 1.08 [0.93, 1.26]
4 studies · 3044 participants
Moderate

Antibiotics vs placebo

All‐cause mortality WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…

Antibiotics showed no clear difference in all‐cause mortality WMD of compared with placebo (moderate certainty).

1 finding from 1 review

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
OR 0.87 [0.66, 1.15]
6 studies · 3309 participants
Moderate

Oxytocin vs ergot alkaloids

Maternal mortality ‐ not reported · women in the third stage of labour

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oxytocin + ergometrine vs ergot alkaloids

Maternal mortality ‐ not reported · women in the third stage of labour

1 finding from 1 review

Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 807 participants
Moderate

Oxytocin vs no uterotonics or placebo

Maternal mortality ‐ not reported · women in the third stage of labour

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any glucocorticoid vs placebo

Mortality within the longest · Children having heart surgery with cardiopulmonary bypass

Glucocorticoid showed no clear difference in all‐cause mortality at longest compared with placebo (moderate certainty).

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
RR 0.83 [0.33, 2.07]
5 studies · 313 participants
Moderate

Intervention not reported

All‐cause mortality ‐ not reported · people with haematological disorders undergoing intensive chemotherapy or stem cell transplantation

The review found no eligible studies for this question.

1 finding from 1 review

Alternatives, and adjuncts, to prophylactic platelet transfusion for people with haematological malignancies… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Macrolide+tetracycline vs macrolides

All‐cause mortality 60 weeks (end of study) · patients with chronic obstructive pulmonary disease

It is very uncertain whether macrolide+tetracycline changes all‐cause mortality 60 weeks (end of study) compared with macrolide (very low certainty).

1 finding from 1 review

Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
OR 1.63 [0.38, 7.02]
1 study · 198 participants
Very low

Thromboelastography threshold vs standard of care (laboratory parameters)

All‐cause mortality up to 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

All‐cause mortality within 30 days of surgery – not reported · people with a low platelet count

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic platelet transfusions prior to surgery for people with a low platelet count 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found