Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

15 questions · 15 findings · 12 reviews · Headline outcomes only

No studies found 1 · 6.7%GRADE not reported 0 · 0%Very low 6 · 40%Low 3 · 20%Moderate 5 · 33.3%High 0 · 0%

LAMA add‐on vs long‐acting beta2‐agonists (LABA) add‐on

Adverse events (all) · adults with asthma not well controlled on ICS

Long‐acting muscarinic antagonists (LAMA) add‐on showed no clear difference in adverse events (all) compared with long‐acting beta2‐agonists (LABA) add‐on (moderate certainty).

1 finding from 1 review

Complete revascularisation vs culprit‐only revascularisation

Overall adverse events (pooled short and long term) · people with STEMI and MVD.

It is very uncertain whether complete revascularisation changes overall adverse events (pooled short and long term) compared with culprit‐only revascularisation (very low certainty).

1 finding from 1 review

Summary of findings: Any alternative model of care vs usual care

Falls · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)

It is very uncertain whether summary of findings: Any alternative model of care changes adverse events/falls: proportion of residents with a fall at longest compared with usual care (very low certainty).

1 finding from 1 review