Cochrane · systematic review · CD013323

Non‐Chinese herbal medicines for functional dyspepsia

Báez, G, Vargas, C, Arancibia, M, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 8.3%Low 5 · 41.7%Moderate 6 · 50%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

STW5 (Iberogast) compared to placebo for functional dyspepsia

Population: participants with functional dyspepsia
4 questions
OutcomeEffectEvidenceStatus / GRADE
Global symptoms of dyspepsia
STW5 (Iberogast) vs placebo
no estimate extracted5 studies · 814 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Global symptoms of dyspepsia (responders)
STW5 (Iberogast) vs placebo
RR 1.55 [0.98, 2.47]2 studies · 324 participantsLow
Downgraded: risk of bias, imprecision
Adverse events Assessed clinically
STW5 (Iberogast) vs placebo
RR 0.92 [0.52, 1.64]4 studies · 786 participantsLow
Downgraded: risk of bias, imprecision
Quality of life
STW5 (Iberogast) vs placebo
no estimate extracted1 study · 52 participantsLow
Downgraded: risk of bias, imprecision

Peppermint/caraway oil compared to placebo for functional dyspepsia

Population: participants with functional dyspepsia
4 questions
OutcomeEffectEvidenceStatus / GRADE
Global symptoms of dyspepsia
Peppermint/caraway oil vs placebo
no estimate extracted2 studies · 210 participantsModerate
Downgraded: risk of bias
Global symptoms of dyspepsia (responders)
Peppermint/caraway oil vs placebo
RR 1.53 [1.3, 1.81]3 studies · 305 participantsModerate
Downgraded: risk of bias
Adverse events Assessed clinically
Peppermint/caraway oil vs placebo
RR 1.56 [0.69, 3.53]3 studies · 305 participantsLow
Downgraded: risk of bias, imprecision
Quality of life
Peppermint/caraway oil vs placebo
no estimate extracted1 study · 99 participantsModerate
Downgraded: risk of bias

Curcuma longa compared to placebo

Population: participants with functional dyspepsia
4 questions
OutcomeEffectEvidenceStatus / GRADE
Global symptoms of dyspepsia
Curcuma longa vs placebo
no estimate extracted2 studies · 110 participantsModerate
Downgraded: imprecision
Global symptoms of dyspepsia (responders)
Curcuma longa vs placebo
RR 1.5 [1.06, 2.11]1 study · 76 participantsLow
Downgraded: risk of bias, imprecision
Adverse events Assessed clinically
Curcuma longa vs placebo
RR 1.26 [0.51, 3.08]1 study · 89 participantsModerate
Downgraded: imprecision
Quality of life
Curcuma longa vs placebo
no estimate extracted1 study · 89 participantsModerate
Downgraded: imprecision