Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

59 questions · 59 findings · 33 reviews · Headline outcomes only

No studies found 8 · 13.6%GRADE not reported 8 · 13.6%Very low 23 · 39%Low 12 · 20.3%Moderate 7 · 11.9%High 1 · 1.7%

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: hypertension · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: hypertension compared with 2 months of therapy (moderate certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: Cushing's syndrome · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: Cushing's syndrome compared with 2 months of therapy (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ More time vs less time

Serious adverse events/death: medium‐term outcomes · rehabilitation (medium‐term outcomes)

It is very uncertain whether summary of findings table ‐ More time changes serious adverse events/death: medium‐term outcomes compared with less time (very low certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: psychological disorders · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: psychological disorders compared with 2 months of therapy (low certainty).

1 finding from 1 review