Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

39 questions · 39 findings · 19 reviews · Musculoskeletal

No studies found 15 · 38.5%GRADE not reported 6 · 15.4%Very low 6 · 15.4%Low 5 · 12.8%Moderate 5 · 12.8%High 2 · 5.1%

Hand exercise vs no exercise

Adverse events · patients with hand osteoarthritis

It is very uncertain whether hand exercise changes adverse events compared with no exercise (very low certainty).

1 finding from 1 review

Exercise vs no intervention

Withdrawals due to adverse events · adults with ankylosing spondylitis

Exercise programmes showed no clear difference in withdrawals because of adverse events Exercise programme duration:… compared with no intervention (low certainty).

1 finding from 1 review

Hand exercise vs no exercise

Withdrawals due to adverse events · patients with hand osteoarthritis

It is very uncertain whether hand exercise changes withdrawal due to adverse events compared with no exercise (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Adverse events · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… showed no clear difference in adverse events compared with land‐based exercise therapy (low certainty).

1 finding from 1 review

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Adverse events · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise following joint distension leads to lower adverse events compared with sham ultrasound following joint distension (high certainty).

1 finding from 1 review

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs placebo adjunctive therapies

Adverse events · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… showed no clear difference in adverse events compared with placebo adjunctive therapies (low certainty).

1 finding from 1 review