Cochrane · systematic review · CD003832

Exercise for rheumatoid arthritis of the hand

Williams, MA, Srikesavan, C, Heine, PJ, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
17
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 5.6%Very low 6 · 33.3%Low 0 · 0%Moderate 7 · 38.9%High 4 · 22.2%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Exercise compared to no exercise for rheumatoid arthritis of the hand

Population: rheumatoid arthritis of the hand
18 questions
OutcomeEffectEvidenceStatus / GRADE
Hand function ‐ short term (less than 3 months) Grip function test scale of 0 to 80 points (higher score indicates better grip function)
Exercise vs no exercise
no estimate extracted1 study · 24 participantsVery low
Downgraded: risk of bias, imprecision
Hand function ‐ medium term (3 to 11 months) Overall hand function subscale of the Michigan Hand Questionnaire, 0 to 100 (higher scores mean better hand function)
Exercise vs no exercise
no estimate extracted1 study · 449 participantsModerate
Downgraded: risk of bias
Hand function ‐ long term (12 months and beyond) Overall hand function subscale of the Michigan Hand Questionnaire, 0 to 100 (higher scores mean better hand function)
Exercise vs no exercise
no estimate extracted1 study · 438 participantsModerate
Downgraded: risk of bias
Pain ‐ short term (less than 3 months) visual analogue scale (0 to 100 mm, higher score means more pain)
Exercise vs no exercise
no estimate extracted2 studies · 124 participantsVery low
Downgraded: risk of bias, imprecision
Pain ‐ medium term (3 to 11 months) Pain subscale of Michigan Hand Outcomes Questionnaire (0 to 100 points, higher score means more pain)
Exercise vs no exercise
no estimate extracted1 study · 445 participantsModerate
Downgraded: risk of bias
Pain ‐ long term (12 months and beyond) Pain subscale of Michigan Hand Outcomes Questionnaire (0 to 100 points, higher score means more pain)
Exercise vs no exercise
no estimate extracted1 study · 437 participantsModerate
Downgraded: risk of bias
Hand impairment ‐ power grip strength (kg) ‐ left hand ‐ short term (less than 3 months)
Exercise vs no exercise
no estimate extracted3 studies · 141 participantsVery low
Downgraded: risk of bias, imprecision
Hand impairment ‐ power grip strength (kg) ‐ right hand ‐ short term (less than 3 months)
Exercise vs no exercise
no estimate extracted3 studies · 141 participantsVery low
Downgraded: risk of bias, imprecision
Hand impairment ‐ power grip strength of both hands (kg) ‐ medium term (3 to 11 months)
Exercise vs no exercise
no estimate extracted1 study · 400 participantsHigh
Hand impairment ‐ power grip strength of both hands (kg) ‐ long term (12 months and beyond)
Exercise vs no exercise
no estimate extracted1 study · 355 participantsHigh
Hand impairment ‐ pinch grip strength (kg) ‐ left hand ‐ short term (less than 3 months)
Exercise vs no exercise
no estimate extracted2 studies · 120 participantsVery low
Downgraded: risk of bias, imprecision
Hand impairment ‐ pinch grip strength (kg) ‐ right hand ‐ short term (less than 3 months)
Exercise vs no exercise
no estimate extracted2 studies · 120 participantsVery low
Downgraded: risk of bias, imprecision
Hand impairment ‐ pinch grip strength of both hands (kg) ‐ medium term (3 to 11 months)
Exercise vs no exercise
no estimate extracted1 study · 396 participantsHigh
Hand impairment ‐ pinch grip strength of both hands (kg) ‐ long term (12 months and beyond)
Exercise vs no exercise
no estimate extracted1 study · 351 participantsHigh
ACR50 response
Exercise vs no exercise
no estimate extracted0 studies · 0 participantsUngraded
Participant adherence ‐ medium term (3 to 11 months)
Exercise vs no exercise
RR 1.31 [1.15, 1.48]1 study · 438 participantsModerate
Downgraded: risk of bias
Participant adherence ‐ long term (12 months and beyond)
Exercise vs no exercise
RR 1.09 [0.93, 1.28]1 study · 422 participantsModerate
Downgraded: risk of bias
Adverse events due to exercise
Exercise vs no exercise
no estimate extracted1 study · 490 participantsModerate
Downgraded: risk of bias