Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

77 questions · 78 findings · 28 reviews

No studies found 16 · 20.5%GRADE not reported 7 · 9%Very low 23 · 29.5%Low 10 · 12.8%Moderate 21 · 26.9%High 1 · 1.3%

Summary of findings table ‐ Recombinant activated factor VII vs placebo/open control

All serious adverse events · adults with acute spontaneous intracerebral haemorrhage

It is very uncertain whether summary of findings table ‐ Recombinant activated factor VII changes all serious adverse events compared with placebo/open control (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Withdrawals due to adverse events · Induction of Remission in Medically Refractory Crohn's Disease

It is very uncertain whether summary of findings table ‐ Stem Cell changes withdrawal due to adverse events compared with placebo or Control (very low certainty).

1 finding from 1 review

Summary of findings: whole‐body cryotherapy (WBC) vs control (no WBC or passive rest)

Adverse events · physically‐active adults partaking in exercise designed to produce delayed onset muscle soreness (most trial participants were male)

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Bladder training vs anticholinergics

Number of any adverse events: immediately after treatment · overactive bladder

It is very uncertain whether summary of findings table ‐ Bladder training changes number of any adverse events: immediately after treatment compared with anticholinergics (very low certainty).

1 finding from 1 review

Summary of findings: Defibrotide vs no treatment

Frequency of adverse events ( · Children undergoing stem cell transplant with malignant and non‐malignant diseases and risk factors for hepatic veno‐occlusive disease

It is very uncertain whether summary of findings: Defibrotide changes frequency of adverse events ( compared with no treatment (very low certainty).

1 finding from 1 review