Cochrane · systematic review · CD009789

Antioxidants for preventing and reducing muscle soreness after exercise

Ranchordas, MK, Rogerson, D, Soltani, H, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Bone, Joint and Muscle TraumaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 1 · 14.3%Low 3 · 42.9%Moderate 2 · 28.6%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings: antioxidants versus placebo

Population: mainly physically active individuals1 partaking in exercise2 designed to produce delayed onset muscle soreness
7 questions
OutcomeEffectEvidenceStatus / GRADE
Muscle soreness
Summary of findings: antioxidants vs placebo
no estimate extracted21 studies · 525 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Muscle soreness
Summary of findings: antioxidants vs placebo
no estimate extracted41 studies · 936 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Muscle soreness
Summary of findings: antioxidants vs placebo
no estimate extracted45 studies · 1047 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Muscle soreness
Summary of findings: antioxidants vs placebo
no estimate extracted28 studies · 657 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Muscle soreness
Summary of findings: antioxidants vs placebo
no estimate extracted17 studies · 436 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Subjective recovery
Summary of findings: antioxidants vs placebo
no estimate extractedNRNo studies
Adverse events
Summary of findings: antioxidants vs placebo
no estimate extracted9 studies · 216 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency