Cochrane · systematic review · CD010516
Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract surgery
Juthani, VV, Clearfield, E, Chuck, RS · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
5
No studies
9
Included studies
NR
No studies 9 · 64.3%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 21.4%Moderate 2 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings for NSAIDs versus corticosteroids
Population: people who received phacoemulsification
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraocular inflammation measured by anterior chamber cell and flare 1 week Summary of findings for NSAIDs vs corticosteroids | no estimate extracted | 3 studies · 174 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Intraocular inflammation measured by proportion of participants with corneal edema 1 week Summary of findings for NSAIDs vs corticosteroids | RR 0.77 [0.26, 2.29] | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Proportion of participants with best‐corrected visual acuity of 20/40 1 week Summary of findings for NSAIDs vs corticosteroids | no estimate extracted | NR | No studies |
Proportion of participants with cystoid macular edema 1 week Summary of findings for NSAIDs vs corticosteroids | RR 0.26 [0.17, 0.41] | 4 studies · 291 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Time to cessation of treatment Summary of findings for NSAIDs vs corticosteroids | no estimate extracted | NR | No studies |
Adverse events Summary of findings for NSAIDs vs corticosteroids | no estimate extracted | NR | No studies |
Economic outcomes Summary of findings for NSAIDs vs corticosteroids | no estimate extracted | NR | No studies |
Summary of findings for NSAIDs plus corticosteroids versus corticosteroids alone
Population: people who received phacoemulsification
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraocular inflammation measured by anterior chamber cell and flare 1 week Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone | no estimate extracted | NR | No studies |
Intraocular inflammation measured by proportion of participants with corneal edema 1 week Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone | RR 1.07 [0.98, 1.16] | 1 study · 138 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Proportion of participants with best‐corrected visual acuity of 20/40 1 week Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone | no estimate extracted | NR | No studies |
Proportion of participants with cystoid macular edema 1 week Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone | RR 0.17 [0.03, 0.97] | 2 studies · 220 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Time to cessation of treatment Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone | no estimate extracted | NR | No studies |
Adverse events Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone | no estimate extracted | NR | No studies |
Economic outcomes Summary of findings for NSAIDs plus corticosteroids vs corticosteroids alone | no estimate extracted | NR | No studies |