Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

488 questions · 501 findings · 191 reviews

No studies found 126 · 25.1%GRADE not reported 124 · 24.8%Very low 104 · 20.8%Low 89 · 17.8%Moderate 49 · 9.8%High 9 · 1.8%

Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo

Adverse events: worsening of hypertension · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: increase in blood pressure compared with placebo (very low certainty).

1 finding from 1 review