Side effects · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)
1 finding from 1 review
Not estimable (5 studies). Adverse effects were assessed in five studies, but they used different outcome measures, so meta-analysis was not appropriate. The main harm identified was soft-tissue trauma to the gingival…
5 studies
GRADE not reported
Adverse effects (dropouts) · patients with major depression
Antidepressants plus benzodiazepines probably leads to lower adverse effects (dropouts) compared with antidepressants alone (moderate certainty).
1 finding from 1 review
Adverse effects: hot flush · premenopausal women with malignant conditions, receiving GnRH agonist before or in parallel to chemotherapy
It is very uncertain whether gnRH agonist plus chemotherapy changes adverse effects: hot flush compared with chemotherapy alone (very low certainty).
1 finding from 1 review
Adverse events: hypertension · minimal change disease in adults with nephrotic syndrome
Calcineurin inhibitors ± oral steroids showed no clear difference in adverse effects: hypertension compared with oral steroids alone (low certainty).
1 finding from 1 review
Adverse effects: vaginal dryness · premenopausal women with malignant conditions, receiving GnRH agonist before or in parallel to chemotherapy
GnRH agonist plus chemotherapy showed no clear difference in adverse effects: vaginal dryness compared with chemotherapy alone (moderate certainty).
1 finding from 1 review
Adverse effects: serious or other · adults with nasal haemorrhage (epistaxis)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects: exposure keratopathy · patients age 10 years and older with periorbital or orbital cellulitis
It is very uncertain whether standard treatment plus systemic corticosteroids changes adverse effects: exposure keratopathy compared with standard treatment alone (very low certainty).
1 finding from 1 review
Side effects or other adverse events · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)
No adverse effects were reported in any of the seven included studies (ungraded).
1 finding from 1 review
Other adverse effects: local irritation · allergic rhinitis
1 finding from 1 review
Nausea · people with epilepsy
Summary of findings: catgut implantation at acupoints plus… showed no clear difference in frequency of adverse effects ‐ nausea ( compared with antiepileptic drugs alone (low certainty).
1 finding from 1 review
Nausea · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in frequency of adverse effects ‐ nausea ( compared with valproate alone (low certainty).
1 finding from 1 review
Frequency of adverse effects ‐ malaise ( · people with epilepsy
Summary of findings: catgut implantation at acupoints plus… showed no clear difference in frequency of adverse effects ‐ malaise ( compared with antiepileptic drugs alone (low certainty).
1 finding from 1 review
Frequency of adverse effects ‐ malaise ( · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in frequency of adverse effects ‐ malaise ( compared with valproate alone (low certainty).
1 finding from 1 review
Frequency of adverse effects ‐ anorexia ( · people with epilepsy
Summary of findings: catgut implantation at acupoints plus… showed no clear difference in frequency of adverse effects ‐ anorexia ( compared with antiepileptic drugs alone (low certainty).
1 finding from 1 review
Frequency of adverse effects ‐ dizziness ( · people with epilepsy
Summary of findings: catgut implantation at acupoints plus… may leads to lower frequency of adverse effects ‐ dizziness ( compared with antiepileptic drugs alone (low certainty).
1 finding from 1 review
Frequency of adverse effects ‐ dizziness ( · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in frequency of adverse effects ‐ dizziness ( compared with valproate alone (low certainty).
1 finding from 1 review
Adverse effects: diabetes or hyperglycaemia · minimal change disease in adults with nephrotic syndrome
Calcineurin inhibitors ± oral steroids showed no clear difference in adverse effects: diabetes or hyperglycaemia compared with oral steroids alone (low certainty).
1 finding from 1 review
Adverse effects (including quality of life) · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
1 finding from 1 review
This comparison was only made in 1 study which reported no serious adverse events associated with HBO therapy. Quality of life measures (oral status, functioning, satisfaction) showed emotional functioning and pain…
1 study · 26 participants
Very low
Frequency of adverse effects ‐ sleepiness ( · participants with generalised epilepsy
Summary of findings: needle acupuncture plus valproate showed no clear difference in frequency of adverse effects ‐ sleepiness ( compared with valproate alone (low certainty).
1 finding from 1 review
Any other adverse effects related to treatment · people with thalassaemia (any age)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found