Pre‐eclampsia · pregnant women and their infants..
Vitamin D + calcium supplementation probably leads to lower pre‐eclampsia compared with placebo or no intervention (moderate certainty).
1 finding from 1 review
Gestational diabetes · pregnant women and their infants..
It is very uncertain whether vitamin D + calcium supplementation changes gestational diabetes compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Pre‐eclampsia · women during pregnancy
A dose of vitamin D 601 IU or higher showed no clear difference in pre‐eclampsia compared with 600 IU or lower alone or with other nutrients (low certainty).
1 finding from 1 review
Gestational diabetes · women during pregnancy
A dose of vitamin D 601 IU or higher probably leads to lower gestational diabetes compared with 600 IU or lower alone or with other nutrients (moderate certainty).
1 finding from 1 review
Preterm birth · women during pregnancy
A dose of vitamin D 601 IU or higher showed no clear difference in preterm birth compared with 600 IU or lower alone or with other nutrients (low certainty).
1 finding from 1 review
Low birthweight · women during pregnancy
It is very uncertain whether A dose of vitamin D 601 IU or higher changes low birthweight compared with 600 IU or lower alone or with other nutrients (very low certainty).
1 finding from 1 review
Rate of exacerbations requiring systemic corticosteroids · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more exacerbations treated… compared with placebo (high certainty).
1 finding from 1 review
Patients with severe exacerbations (requiring hospitalisation or ER visit) · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more exacerbations requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Asthma control · children and adults with predominantly mild to moderate asthma
1 finding from 1 review
FEV1 % predicted · children and adults with predominantly mild to moderate asthma
1 finding from 1 review
Proportion of participants with one or more serious adverse events due to any cause · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more serious adverse events… compared with placebo (high certainty).
1 finding from 1 review
People with fatal asthma exacerbation. · children and adults with predominantly mild to moderate asthma
1 finding from 1 review
Withdrawals (parallel group trials/first arm cross‐over trials) · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in withdrawals from trial compared with placebo (high certainty).
1 finding from 1 review
Death at hospital discharge · individuals with moderate to severe disease
1 finding from 1 review
Improvement of clinical status · individuals with moderate to severe disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Worsening of clinical status · individuals with moderate to severe disease
Summary of Findings Table ‐ Vitamin D showed no clear difference in worsening of clinical status compared with placebo or standard care alone (low certainty).
1 finding from 1 review
Quality of life, including fatigue and neurological functioning; · individuals with moderate to severe disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events: all grades · individuals with moderate to severe disease
It is very uncertain whether summary of Findings Table ‐ Vitamin D changes adverse events (any grade) compared with placebo or standard care alone (very low certainty).
1 finding from 1 review
Serious adverse events · individuals with moderate to severe disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serum/plasma retinol (μmol/L) · general population over 2 years of age
1 finding from 1 review