Question · asked by 1 review

Vitamin D plus calcium vs placebo or no intervention: Pre‐eclampsia

Population
pregnant women and their infants..
Intervention
Vitamin D plus calcium
Comparison
placebo or no intervention
Outcome
Pre‐eclampsia

Vitamin D + calcium supplementation probably leads to lower pre‐eclampsia compared with placebo or no intervention (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Vitamin D + calcium supplementation vs placebo or no intervention
Pre‐eclampsia · pregnant women and their infants..
Vitamin D + calcium supplementation probably leads to lower pre‐eclampsia compared with placebo or no intervention (moderate certainty).
Vitamin D supplementation for women during pregnancy (2019) · Cochrane Headline outcomes only
RR 0.5 [0.32, 0.78]4 studies · 1174 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Vitamin D supplementation for women during pregnancy
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.