Blood transfusion · patients with upper gastrointestinal bleeding
It is very uncertain whether tranexamic acid changes transfusion Number needing blood transfusion compared with placebo (very low certainty).
1 finding from 1 review
Blood transfusion · patients with upper gastrointestinal bleeding
Tranexamic acid may leads to lower transfusion Number of participants who required at least 1 blood… compared with cimetidine or lansoprazole (low certainty).
1 finding from 1 review
Severity of re‐bleeding: proportion of patients requiring blood transfusion within 10 days · adults with nasal haemorrhage (epistaxis)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Severity of re‐bleeding: proportion of patients requiring blood transfusion within 10 days · adults with nasal haemorrhage (epistaxis)
Tranexamic acid showed no clear difference in severity of re‐bleeding: proportion of patients requiring blood… compared with placebo plus usual care or usual care alone (low certainty).
1 finding from 1 review
Risk of requiring allogeneic blood transfusion (30 days post‐surgery) · people undergoing definitive fixation of hip, pelvic and long bone fractures
It is very uncertain whether topical tranexamic acid changes risk of requiring allogeneic blood transfusion (30 days post‐surgery) compared with placebo (very low certainty).
1 finding from 1 review
Blood transfusion · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in blood transfusion (any) compared with placebo or standard care alone (moderate certainty).
1 finding from 1 review
Risk of requiring allogeneic blood transfusion (30 days post‐surgery) · people undergoing definitive fixation of hip, pelvic and long bone fractures
Intravenous tranexamic acid may leads to lower risk of requiring allogeneic blood transfusion (30 days post‐surgery) compared with placebo (low certainty).
1 finding from 1 review
Major bleeding, requiring transfusion of packed red blood cells · People with haemophilia (A or B) undergoing minor oral surgery or dental extractions
1 finding from 1 review
Major bleeding, requiring transfusion of packed red blood cells · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in major bleeding requiring transfusion of packed red blood cells compared with standard care (usual local haemostatic measures: gelatin sponge and…; GRADE not reported.
1 finding from 1 review
Major bleeding, requiring transfusion of packed red blood cells · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in major bleeding requiring transfusion of packed red blood cells compared with placebo (placebo solution/mouthwash); GRADE not reported.
1 finding from 1 review