Adverse events · adults with a confirmed diagnosis of mild COVID‐19, of whom only 10% (219/2132) participants had received ≥ 1 vaccination
Inhaled corticosteroids plus standard care showed no clear difference in adverse events compared with standard care (with or without placebo) (low certainty).
1 finding from 1 review
Infections · adults with a confirmed diagnosis of mild COVID‐19, of whom only 10% (219/2132) participants had received ≥ 1 vaccination
Inhaled corticosteroids plus standard care showed no clear difference in infections compared with standard care (with or without placebo) (low certainty).
1 finding from 1 review
Change in QoL SNOT‐20 · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Complications of surgery · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
FEV1 % predicted: absolute change from baseline · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Eradication of bacterial infection · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Clinical improvement(visual analogue scale) · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
Pulmonary exacerbations · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
1 finding from 1 review
All‐cause mortality · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Perinatal mortality · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids leads to lower perinatal death (composite of fetal death (in utero death) and… compared with placebo or no treatment (high certainty).
1 finding from 1 review
RR 0.85 [0.77, 0.93]
Studies not reported
High
Neonatal death (baby born alive at any gestation and dies within 28 days) · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids leads to lower neonatal death (infants born with signs of life who die within the… compared with placebo or no treatment (high certainty).
1 finding from 1 review
RR 0.78 [0.7, 0.87]
Studies not reported
High
Respiratory distress syndrome · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids leads to lower respiratory distress syndrome№ of participants: 11,183(26 RCTs) compared with placebo or no treatment (high certainty).
1 finding from 1 review
RR 0.71 [0.65, 0.78]
Studies not reported
High
Intraventricular haemorrhage · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids probably leads to lower intraventricular haemorrhage (IVH)№ of participants: 8475(12 RCTs) compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
RR 0.58 [0.45, 0.75]
Studies not reported
Moderate
Mean birthweight · infants born of women at risk of preterm birth
1 finding from 1 review
no estimate extracted
Studies not reported
High
Developmental delay in childhood№ of participants: 600 (3 RCTs). Age at · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids probably leads to lower developmental delay in childhood№ of participants: 600 (3 RCTs). Age… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
RR 0.51 [0.27, 0.97]
Studies not reported
Moderate
FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis
1 finding from 1 review
FVC (% predicted) Change from baseline · adults and children with cystic fibrosis
1 finding from 1 review
BHR: change in PC20 values · adults and children with cystic fibrosis
1 finding from 1 review
Change in exercise tolerance · adults and children with cystic fibrosis
1 finding from 1 review
Respiratory exacerbations: number of days on intravenous antibiotics for respiratory exacerbations · adults and children with cystic fibrosis
It is very uncertain whether summary of findings: inhaled corticosteroids changes respiratory exacerbations: number of days on intravenous antibiotics… compared with placebo (very low certainty).
1 finding from 1 review