Question · asked by 1 review

Corticosteroids vs placebo or no treatment: Respiratory distress syndrome

Neonatal and child outcomes: corticosteroids leads to lower respiratory distress syndrome№ of participants: 11,183(26 RCTs) compared with placebo or no treatment (high certainty).

What each review found

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FindingEffectStudiesGRADE certainty
Neonatal and child outcomes: corticosteroids vs placebo or no treatment
Respiratory distress syndrome№ of participants: 11,183(26 RCTs) · infants born of women at risk of preterm birth
Neonatal and child outcomes: corticosteroids leads to lower respiratory distress syndrome№ of participants: 11,183(26 RCTs) compared with placebo or no treatment (high certainty).
Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth (2020) · Cochrane Headline outcomes only
RR 0.71 [0.65, 0.78]Not reportedHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.