Cochrane · systematic review · CD014084
Surgery for nasal polyposis in cystic fibrosis
Almeida, PRibeiro Lopes, Person, OC, Puga, MES, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Cystic Fibrosis and Genetic DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 6 · 85.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings for nasal irrigation with topical steroids plus sinus surgery compared to nasal irrigation with topical steroids alone for nasal polyposis in people with cystic fibrosis
Population: children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in QoL SNOT‐20 Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone | no estimate extracted | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Complications of surgery Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone | no estimate extracted | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Change in lung function (FEV1 % predicted) Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone | no estimate extracted | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Eradication of bacterial infection Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone | no estimate extracted | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Clinical improvement(visual analogue scale) Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone | no estimate extracted | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Frequency of pulmonary exacerbations Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone | no estimate extracted | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Mortality Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone | no estimate extracted | NR | No studies |