Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

240 questions · 263 findings · 36 reviews

No studies found 18 · 6.8%GRADE not reported 92 · 35%Very low 68 · 25.9%Low 59 · 22.4%Moderate 21 · 8%High 5 · 1.9%

Anticipated high responders: higher vs lower dose of FSH

IU vs 100 IU · women undergoing IVF/ICSI who are anticipated to have a hyper‐response to stimulation based on at least one ORT measure

Anticipated high responders: higher showed no clear difference in IU vs 100 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Children: higher dose/longer course vs lower dose/shorter course

Exacerbations · children with acute asthma

Children: higher dose/longer course showed no clear difference in new exacerbation during compared with lower dose/shorter course (low certainty).

2 findings from 1 review

Higher parental education (tertiary) vs Lower parental education (reference)

Early childhood caries (ECC) · Children aged 0-5 years in North Africa

Paternal tertiary education was associated with lower odds of ECC (OR 0.381).

3 findings from 1 review

Higher mean patient age (per 1 year) vs Lower mean patient age (per 1-year decrement)

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the mandible, mean patient age was not significantly associated with space closure odds (OR 0.59 per year; not GRADE-rated).

1 finding from 1 review

Higher parental / maternal education vs Lower parental education (reference)

Oral health-related quality of life · Adolescents (10-19 years)

Higher parental education is associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents from families with higher incomes and higher levels of maternal education have better OHRQoL scores [34]. Children from families with high income, parental education and family economy had better OHRQoL [42].
    Studies not reported
    GRADE not reported

Anticipated normal responders: higher vs lower dose of FSH

IU vs 100 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure

Anticipated normal responders: higher showed no clear difference in IU vs 100 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated normal responders: higher vs lower dose of FSH

225/200 IU vs 150 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure

Anticipated normal responders: higher showed no clear difference in 225/200 IU vs 150 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated normal responders: higher vs lower dose of FSH

IU vs 225 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure

Anticipated normal responders: higher showed no clear difference in IU vs 225 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review