Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

449 questions · 486 findings · 74 reviews

No studies found 34 · 7%GRADE not reported 73 · 15%Very low 127 · 26.1%Low 158 · 32.5%Moderate 69 · 14.2%High 25 · 5.1%

Early childhood caries (ECC) vs Caries-free controls

Relative abundance of Veillonella spp. · Young children with early childhood caries and caries-free controls

Veillonella spp. mean relative abundance was higher in ECC children, without a comparative effect estimate or CI.

4 findings from 2 reviews · compare the 2 reviews
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Early childhood caries (ECC) vs Caries-free controls

Number of detected salivary bacterial genera · Young children with early childhood caries and caries-free controls

Fewer salivary bacterial genera were reported in the caries-affected group, without a comparative effect estimate or CI.

1 finding from 1 review

Early childhood caries (ECC) vs Caries-free controls

Relative abundance of dominant salivary microbial community (7 genera) · Young children with early childhood caries and caries-free controls

The reported multi-genus community had similar relative abundance in caries-affected and caries-free children, without a comparative effect estimate or CI.

1 finding from 1 review

Early childhood caries (ECC) vs Caries-free controls

Streptococcus mutans and Veillonella spp. levels · Young children with early childhood caries and caries-free controls

Veillonella spp. levels were reported as substantially greater in caries subjects, but the review gave no numerical effect estimate or CI.

1 finding from 1 review

Early childhood caries (ECC) vs NA (within-white-spot-lesion correlation, not a caries vs caries-free comparison)

Correlation of Veillonella spp. with acidogenic streptococci · Young children with early childhood caries and caries-free controls

Veillonella spp. levels were correlated with acidogenic streptococci in white spot lesions (r²=0.38); no CI was reported.

1 finding from 1 review

Planned early birth vs expectant management

Admission to neonatal intensive care unit · preterm prelabour rupture of membranes (PPROM)

Planned early birth probably leads to higher admission to neonatal intensive care compared with expectant management (moderate certainty).

1 finding from 1 review

Planned early birth vs expectant management

Length of maternal hospital stay (days) · preterm prelabour rupture of membranes (PPROM)

Planned early birth showed no clear difference in length of hospital stay (maternal) compared with expectant management (moderate certainty).

1 finding from 1 review

Planned early birth vs expectant management

Maternal infectious morbidity (chorioamnionitis and/or endometritis) · women with prelabour rupture of membranes at term (37 weeks' gestation or later)

Planned early birth may leads to lower maternal infectious morbidity (chorioamnionitis and/or endometritis) compared with expectant management (low certainty).

1 finding from 1 review