Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

479 questions · 510 findings · 52 reviews

No studies found 99 · 19.4%GRADE not reported 64 · 12.5%Very low 144 · 28.2%Low 146 · 28.6%Moderate 57 · 11.2%High 0 · 0%

Therapist‐supported ICBT vs waiting list, attention, information, or online discussion group only control

Clinically important improvement in anxiety at post‐treatment Indexed by a standardized interview or clinically accepted measure cut‐off score1 · patients with anxiety disorders

Therapist‐supported ICBT may leads to higher clinically important improvement in anxiety at post‐treatment… compared with waiting list, attention, information, or online discussion group… (low certainty).

1 finding from 1 review

CBT plus standard care vs usual care

Global state: 2. Clinically important change (no improvement) ‐ long term · patients with schizophrenia

It is very uncertain whether COMPARISON 1: CBT+ STANDARD CARE changes global state: 2. Clinically important change (no improvement) ‐ long… compared with STANDARD CARE ALONE (very low certainty).

1 finding from 1 review

CBT plus standard care vs usual care

Mental state: General ‐ clinically important change (no improvement) · patients with schizophrenia

It is very uncertain whether COMPARISON 1: CBT+ STANDARD CARE changes mental state: General ‐ clinically important change (no improvement)… compared with STANDARD CARE ALONE (very low certainty).

1 finding from 1 review

CBT plus standard care vs usual care

Adverse events experienced at short or long term ‐ general adverse events 24 weeks' · patients with schizophrenia

It is very uncertain whether COMPARISON 1: CBT+ STANDARD CARE changes adverse events: General: any adverse event compared with STANDARD CARE ALONE (very low certainty).

1 finding from 1 review