Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
Chlorhexidine (CHX) led to lower reduction in level of contamination by particles >5 um (droplets) at… compared with essential oils/herbal mouthwash; GRADE not reported.
4 findings from 1 review
MD -44.1 [-59.12, -29.08]
1 study · 20 participants
GRADE not reported
Bay 1993 compared 0.12% CHX with essential oil mouthwash C (Listerine) at pharynx level (Andersen's level 2), which was considered patient level and hence was not analysed. No pooled estimate or GRADE rating.
1 study
GRADE not reported
MD -12.21 [-15.58, -8.83]
3 studies · 76 participants
Low
Show 1 more finding
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty).
9 findings from 1 review
MD 8.8 [2.7, 14.9]
1 study · 20 participants
Very low
MD 17.4 [11.3, 23.5]
1 study · 20 participants
Very low
MD -11.5 [-18.37, -4.63]
1 study · 20 participants
Very low
Show 6 more findings
MD -8.8 [-14.9, -2.7]
1 study · 20 participants
Very low
MD -2.2 [-9.07, 4.67]
1 study · 20 participants
Very low
MD -30 [-85.86, 25.86]
1 study · 30 participants
Very low
MD -0.2 [-6.3, 5.9]
1 study · 20 participants
Very low
MD 13.6 [6.73, 20.47]
1 study · 20 participants
Very low
MD 4.43 [-2.27, 11.13]
2 studies · 50 participants
Very low
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
5 findings from 1 review
At operator level, because of high heterogeneity (I2 = 98%), the results were not meta-analysed (6 studies, 196 participants). No pooled estimate or GRADE rating.
6 studies · 196 participants
GRADE not reported
MD -632.94 [-1267.33, 1.45]
3 studies · 80 participants
Very low
MD -101.1 [-107.01, -95.19]
1 study · 20 participants
Low
Show 2 more findings
Bay 1993 compared 0.12% CHX with distilled water (30-second rinse) and evaluated the outcome at patient level (Andersen's level 2, oropharynx); the data were not included in the meta-analysis. No pooled estimate or…
1 study
GRADE not reported
At assistant level, because of high heterogeneity (I2 = 96%), the results were not meta-analysed (4 studies, 136 participants). No pooled estimate or GRADE rating.
4 studies · 136 participants
GRADE not reported
Reduction in level of contamination by particles <=5 um (droplet nuclei) at >=2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles <=5 um (droplet… compared with povidone iodine (very low certainty).
2 findings from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with ozonated water (very low certainty).
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
Chlorhexidine (CHX) led to lower reduction in level of contamination by particles >5 um (droplets) at… compared with saline; GRADE not reported.
2 findings from 1 review
MD -668.4 [-1044.45, -292.35]
1 study · 20 participants
GRADE not reported
MD -21.33 [-36.8, -5.86]
1 study · 12 participants
Very low
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with boric acid (very low certainty).
2 findings from 1 review
MD -8.03 [-9.65, -6.41]
1 study · 60 participants
Very low
MD -26.6 [-28.24, -24.96]
1 study · 60 participants
Very low
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with povidone iodine (very low certainty).
2 findings from 1 review
Reduction in level of contamination by particles <=5 um (droplet nuclei) at >=2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles <=5 um (droplet… compared with ozonated water (very low certainty).
2 findings from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
1 finding from 1 review
At operator level, because of high heterogeneity (I2 = 89%), which could not be explained, the results were not meta-analysed (2 studies, 60 participants; Feres 2010, Retamal-Valdes 2017). No pooled estimate or GRADE…
2 studies · 60 participants
GRADE not reported
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
Chlorhexidine showed no clear difference in incidence of VAP compared with potassium permanganate; GRADE not reported.
1 finding from 1 review
RR 0.87 [0.50, 1.52]
2 studies
GRADE not reported
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Chlorhexidine showed no clear difference in mortality compared with potassium permanganate; GRADE not reported.
1 finding from 1 review
RR 1.11 [0.89, 1.38]
2 studies
GRADE not reported
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Chlorhexidine spray vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Proportion of participants with moderate to severe pain 72 hours to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found